Preheat oven to 275 degrees F. Line a rimmed baking sheet with parchment paper (for easy cleanup) or simply coat with nonstick cooking spray.
Empty the entire bag of pretzels into a 1 gallon resealable plastic bag (alternatively, you can put them in a very large mixing bowl.)
In a measuring cup (or bowl), whisk together the vegetable oil, Ranch seasoning mix, dill weed, garlic powder, and cayenne until fully combined.
Drizzle the liquid mixture over the pretzels, seal the bag, and gently shake/toss to fully coat.
Spread out onto the prepared baking sheet.
Bake for 15-20 minutes, stirring once halfway through.
Allow to cool completely (they will crisp up as they cool.) Enjoy!
We prefer these pretzels because their crisscross shape allows for more coverage of the seasoning and they have a buttered quality that is extra delicious. But a 16 ounce bag of pretzel twists is totally fine.
Nutritional information given is an automatic calculation and can vary based on the exact products you use and any changes you make to the recipe. If these numbers are very important to you, I would recommend calculating them yourself.